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Fig.: Humboldt-Universität zu Berlin

Humboldt-Universität zu Berlin - SALSA School of Analytical Sciences Adlershof

Lecture Prof. Peter Fratzl

When May 12, 2015 from 03:00 PM to 05:00 PM (Europe/Berlin / UTC200) iCal
Where Room 0'07, SALSA, IRIS-Building, Berlin-Adlershof

 

 

 

 

 

Multi-mode imaging of bone tissues

 

Mineralized tissues such as bone or dentin from mammals but also calcified exoskeletons of shells of sponge skeletons are hierarchically structured materials with often exceptional mechanical properties. To improve our understanding of the mechanical adaptation of these materials but also improve our insight into growth and healing processes, it is essential to combine various imaging modalities giving structural, compositional and mechanical information on different scales from the nanometer to the macroscopic scale. In addition, bone is a dynamic tissue, which adds time as a fourth dimension. Indeed, bone is continuously undergoing processes of remodeling, during which the local characteristics of organic tissue and mineral particles are changing while bone forming osteoblasts get embedded in the bone matrix becoming osteocytes. The situation is even more complex during bone healing where callus tissue is laid down, matures and eventually gets resorbed or remodeled into bone. The presentation will review ongoing efforts to combine position resolved x-ray diffraction, small-angle scattering and fluorescence spectroscopy with light microscopic imaging, polarized Raman imaging and mechanical mapping. This allows imaging hard and soft components of mineralized tissue from the nano- to the micro-scale and to estimate their properties in relation to the overall architecture of the organ and even the position of cells in the tissue.

 

Prof. Peter Fratzl

Max Planck Institute of Colloids and Interfaces

 

Tuesday, May 12th 2015
3:00 p.m

 

Location: IRIS-Building, Zum Großen Windkanal 6, 12489 Berlin, room 0'07